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Cancer Therapy
Data on cancer therapy reported by researchers at University of Tubingen
September 24th, 2008
Fresh data on cancer are presented in the report 'Matrilysin (MMP-7) is a novel broadly expressed tumor antigen recognized by antigen-specific T cells.' "A prerequisite for the development of vaccination strategies is the identification and characterization of relevant tumor-associated antigen. Using microarray and reverse transcription-PCR analysis, we found matrix metalloproteinase (MMP)-7 to be extensively up-regulated in renal cell carcinomas and expressed in a broad variety of malignant cells," researchers in Tubingen, Germany report. "MMP-7 can promote cancer invasion and angiogenesis by proteolytic cleavage of extracellular matrix and basement membrane proteins,...
Source: Vaccine Weekly (2008-09-24)
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