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Sepsis Vaccines
Scientists at University of California, Department of Pathology discuss research in sepsis vaccines
September 24th, 2008
Investigators publish new data in the report 'Protection of mice against H. somni septicemia by vaccination with recombinant immunoglobulin binding protein subunits.' According to a study from the United States, "Histophilus somni causes bovine pneumonia as well as septicemia and its sequelae but mechanisms of virulence and protective immunity are poorly understood. Since surface immunoglobulin binding proteins are virulence factors, we addressed their role as protective antigens in a mouse model of H. somni septicemia." "Immunoglobulin binding protein A (IbpA), has homology to Bordetella pertussis filamentous hemagglutinin and other large bacterial exoproteins....
Source: Vaccine Weekly (2008-09-24)
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