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Vaccine Weekly

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Immunization



Reports by B.R. Sellman and co-researchers describe recent advances in immunization



September 24th, 2008

According to a study from the United States, "SdrG is a surface-associated fibrinogen binding protein present in most strains of Staphylococcus epidermidis. Surface expression of SdrG was not detected by flow cytometry or immunofluorescence microscopy on S. epidermidis 0-47 grown in nutrient broth or in the presence of human serum. sdrG transcript levels increased I hour following a shift from growth in nutrient broth to growth in the bloodstream of a mouse and resulted in a concomitant increase in protein levels as detected by immunofluorescence microscopy."

"The environmental signal(s) resulting in the increase in expression is elusive, as growth under conditions...


Source: Vaccine Weekly (2008-09-24)

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