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Vaccine Weekly

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Immunization



Researchers at University of Louvain publish new data on immunization



September 24th, 2008

In this recent report, researchers in Brussels, Belgium conducted a study "To protect a naive global population against pandemic influenza, pandemic vaccines should be effective at low antigen doses, because of limited manufacturing capacity. In a multicenter, randomized, blind-observer phase 1 trial, groups of 50 healthy young adults received 2 doses, 21 days apart, of influenza A/Vietnam/1194/2004 NIBRG-14 (H5N1) vaccine containing 1.9, 3.8, 7.5 or 15 mu g of hemagglutinin with oil-in-water emulsion adjuvant or 7.5 mu g of hemagglutinin without adjuvant."

"Safety was monitored to day 42. Homologous hemagglutination-inhibition ( HI) and microneutralization titers were...


Source: Vaccine Weekly (2008-09-24)

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