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Vaccine Weekly

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Enzyme Research



Studies from E.A.G. Reis et al have provided new data on enzyme research



October 1st, 2008

According to recent research published in the Scandinavian Journal of Immunology, "We evaluated the ability of naive monocyte-derived dendritic cells (DC) to sensitize autologous peripheral blood mononuclear cells (PBMC) to the schistosome vaccine candidate MAP4 using a priming in vitro (PIV) assay. MAP4 is a multiple antigen peptide containing B- and T-cell epitopes derived from the glycolytic enzyme triose phosphate isomerase."

"PBMC primed and restimulated with MAP4 first and secondary recalls (MAP4 PIV cells) were examined for cell phenotype and cytokine production. We found that after the first recall stimulation with MAP4, the major cell population was...


Source: Vaccine Weekly (2008-10-01)

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