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Life Sciences
Researchers at Harvard University, Department of Pediatrics target life sciences
October 1st, 2008
New investigation results, 'Effects of flagellin on the functions of follicle-associated epithelium,' are detailed in a study published in The Journal of Infectious Diseases. "Bacterial flagellin activates innate immune responses by signaling through Toll-like receptor 5 and is a potential vaccine adjuvant. Mucosal lymphoid follicles, inductive sites for adaptive mucosal immune responses, are covered by a follicle-associated epithelium (FAE) specialized for the uptake of antigens," scientists writing in the Journal of Infectious Diseases report. "This study demonstrates that mucosal application of Salmonella dublin flagellin enhanced transepithelial...
Source: Vaccine Weekly (2008-10-01)
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