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Vaccine Weekly

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Vaccines



Study findings from A.Y. Chen et al broaden understanding of vaccines



October 8th, 2008

According to a study from Toowoomba, Australia, "Intramuscular immunization of mice with DNA cocktail vaccines, comprising potential protective antigens P36, P46, NrdF, and P97 or P97R1 of Mycoplasma hyopneumoniae, induced strong Th1-polarized immune responses against each antigen, with only P46 eliciting a serum IgG response."

"Subcutaneous immunization with protein cocktail vaccines, surprisingly, induced both Th1-polarized immune response as well as antibody response whereas mice immunized with DNA cocktail vaccines followed by boosting with protein cocktail vaccines generated strong Th1-polarized and humoral immune responses," wrote A.Y. Chen and colleagues.

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Source: Vaccine Weekly (2008-10-08)

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