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Vaccine Weekly

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Dengue Fever Vaccines



Research conducted at J.P. Babu and co-authors has provided new information about dengue fever vaccines



October 8th, 2008

Data detailed in 'Immunogenicity of a recombinant envelope domain III protein of dengue virus type-4 with various adjuvants in mice' have been presented. "Dengue fever, a mosquito borne viral disease, has become a major public health problem with dramatic expansion in recent decades. Several dengue vaccines are at developing stage, none are yet available for humans," scientists in Gwalior, India report.

"There is no vaccine or antiviral therapy available for dengue fever till date. Domain III of envelope protein is involved in binding to host receptors and it contains type and subtype-specific epitopes that elicit virus neutralizing antibodies. Hence domain III is an...


Source: Vaccine Weekly (2008-10-08)

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