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Vaccine Weekly

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Immunization



Research from Sun Yat-Sen University provides new data on immunization



October 8th, 2008

A report, 'Vaccination of Alzheimer's model mice with adenovirus vector containing quadrivalent foldable Abeta(1-15) reduces Abeta burden and behavioral impairment without Abeta-specific T cell response,' is newly published data in Journal of the Neurological Sciences. "Active amyloid beta (Abeta) vaccination has been shown to be effective in clearing cerebral Abeta and improving cognitive function in mouse models of Alzheimer's disease (AD). The meningoencephalitis observed in AD vaccination trial was likely related to excessive T cell-mediated immunity caused by the immunogen Abeta(1-42)," scientists in Guangzhou, People's Republic of China report.

"To avoid...


Source: Vaccine Weekly (2008-10-08)

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