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Rotavirus Genetics

Report summarizes rotavirus genetics study findings from T.DEM. Tavares and co-researchers

Published in Vaccine Weekly, October 8th, 2008

Scientists discuss in 'Molecular characterization of the NSP4 gene of human group A rotavirus samples from the West Central region of Brazil' new findings in rotavirus. "Nonstructural protein 4 (NSP4), encoded by group A rotavirus genome segment 10, is a multifunctional protein and the first recognized virus-encoded enterotoxin. The NSP4 gene has been sequenced, and five distinct genetic groups have been described: genotypes A-E," investigators in Brasil, Brazil report.

"NSP4 genotypes A, B, and C have been detected in humans. In this study, the NSP4-encoding gene of human rotavirus strains of different G and P genotypes collected from children between 1987 and 2003 in...

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