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Vaccines
Data on vaccines published by researchers at University zu Lubeck, Department of Paediatrics
October 8th, 2008
Data detailed in 'Anti-tumor effect of DNA-based vaccination and dSLIM immunomodulatory molecules in mice with Ph+ acute lymphoblastic leukaemia' have been presented. According to recent research published in the journal Vaccine, "Since the prognosis of patients with Philadelphia chromosome positive acute lymphoblastic leukaemia (Ph+ ALL) still remains poor, new relapse prevention strategies are needed. We evaluated the pre-immunization of mice with DNA-based vaccines subsequently challenged by the syngeneic Ph+ ALL cell line BM185." "Ballistic transfer of minimalistic immunogenically defined gene expression (MIDGE) vectors encoding a BCR-ABLp185 fusion specific...
Source: Vaccine Weekly (2008-10-08)
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