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Vaccine Weekly

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Immunization



New immunization study results reported from B. Basso et al



October 15th, 2008

"In our laboratory, we have developed a model of vaccination in mice with Trypanosoma rangeli, a non-pathogenic parasite that shares many antigens with Trypanosoma cruzi. The vaccinated mice were protected against infection with virulent T. cruzi," scientists in Cordoba, Argentina report.

"The goal of the present work was to study the protective activity of strains of T. rangeli of different origin, with the aim of analysing whether this protective capacity is a common feature of T. rangeli. BALB/c mice were vaccinated with live or fixed epimastigotes of two T. rangeli strains, Choachi and SC-58. Vaccinated (VM) and control mice ( CM) were infected with virulent T....


Source: Vaccine Weekly (2008-10-15)

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