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Foot and Mouth Disease
Research from J.K. Mohapatra and co-researchers provides new data on foot and mouth disease
October 15th, 2008
"This study deals with a comparative analysis of complete genome sequences of twenty-one serotype Asia 1 foot-and-mouth disease (FM[D) field viruses isolated over a period of two decades from India, two vaccine strains and seven exotic sequences. The Indian viruses could be grouped in to three distinct lineages at the entire coding region, evolving independently probably under differential selection pressure as evident from the lineage-specific signatures identified," scientists in India report. "This comparison revealed 80% of amino acids at the polyprotein region to be invariant. Twenty-one residues in L, 3A and P1 region were identified to be under positive selection...
Source: Vaccine Weekly (2008-10-15)
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