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Vaccine Weekly

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Adenovirus



Research on adenovirus reported by W.M. Jiang et al



October 15th, 2008

According to a study from Nanjing, People's Republic of China, "Porcine reproductive and respiratory syndrome (PRRS) is one of the most important causes of economic losses of the swine industry. PRRS virus (PRRSV) infection poses a challenge to current vaccination strategies."

"In this study, three replication-defective adenovirus recombinants expressing fusion protein GP3-GP5, GP4-GP5, or GP3-GP4-GP5 were developed as potential vaccine against PRRSV in a mouse model. Six groups of BALB/c mice (24 mice per group) were inoculated subcutaneously twice at 2-week intervals with above mentioned recombinants and other adenoviruses expressing single GP3, GP4, or GP5 protein....


Source: Vaccine Weekly (2008-10-15)

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