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Tuberculosis
New tuberculosis data have been reported by scientists at Oregon Health & Science University
October 15th, 2008
"Screening for latent tuberculosis (TB) infection (LTBI) prior to anti-tumor necrosis factor (TNF) therapy is complicated by the decreased sensitivity of the purified protein derivative tuberculin skin test in immunosuppressed patients, as well as the poor specificity of the tuberculin skin test in bacillus Calmette-Guerin (BCG)-vaccinated patients. Interferon-gamma-release assays that utilize specific TB antigens (e.g," scientists writing in the journal Nature Clinical Practice Rheumatology report. "ESAT-6/CFP-10) have greater specificity for LTBI, but their relative sensitivity is unknown in the setting of immune suppression. Dinser et al. evaluated a novel...
Source: Vaccine Weekly (2008-10-15)
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