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Vaccine Weekly

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Vaccines



Recent findings from Emory Vaccine Center highlight research in vaccines



October 15th, 2008

"Gammaherpesvirus 68 (gamma HV68, or MHV68) is a naturally occurring rodent pathogen that replicates to high titer in cell culture and is amenable to in vivo experimental evaluation of viral and host determinants of gammaherpesvirus disease. However, the inability of MHV68 to transform primary murine B cells in culture, the absence of a robust cell culture latency system, and the paucity of MHV68-positive tumor cell lines have limited an understanding of the molecular mechanisms by which MHV68 modulates the host cell during latency and reactivation," researchers in the United States report.

"To facilitate a more complete understanding of viral and host determinants that...


Source: Vaccine Weekly (2008-10-15)

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