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Hepatitis C Virus
Recent studies by Y.L. Lin and co-authors add new data to hepatitis C virus findings
October 15th, 2008
According to recent research published in the Journal of Virology, "Broad, multispecific CD4(+) and CD8(+) T-cell responses to the hepatitis C virus (HCV), as well as virus-cross-neutralizing antibodies, are associated with recovery from acute infection and may also be associated in chronic HCV patients with a favorable response to antiviral treatment. In order to recapitulate all of these responses in an ideal vaccine regimen, we have explored the use of recombinant HCV polypeptides combined with various Th1-type adjuvants and replication-defective alphaviral particles encoding HCV proteins in various prime/boost modalities in BALB/c mice." "Defective chimeric...
Source: Vaccine Weekly (2008-10-15)
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