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Life Sciences



Research from E. Paulovicova and co-researchers in the area of life sciences described



October 22nd, 2008

According to recent research from Bratislava, Slovakia, "Candida albicans expresses a CR3-related protein (CR3-RP) antigenically, structurally and functionally related to human adhesion glycoprotein, also known as Mac-l, the iC3b receptor, or complement receptor type 3. The purpose of the present study was to analyze the immunogenic properties of a novel CR3-RP glycoconjugate in a rabbit model."

"Cell-mediated responses revealed immunoenhancement triggered by CR3-RP glycoconjugate with respect to expression of IL-2 receptor subunit CD25 on B-lymphocytes and inductive increase of the CD4(+)/CD8(+) ratio compared with unconjugated cell wall mannan (P < 0.001). Active...


Source: Vaccine Weekly (2008-10-22)

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