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Pneumococcal Disease



Researchers' work from University of Alberta focuses on pneumococcal disease



October 22nd, 2008

According to recent research published in the journal Clinical Infectious Diseases, "The 23-valent pneumococcal polysaccharide vaccine (PPV23) is recommended for disease prevention in solid-organ transplant recipients, but it may have suboptimal immunogenicity. It may be possible to enhance immunogenicity by priming the recipient with the 7-valent pneumococcal conjugate vaccine (PCV7), followed by boosting with PPV23."

"We randomized adult liver transplant recipients to receive either (1) PCV7 followed by a PPV23 booster 8 weeks later (the ''primed'' group) or (2) placebo followed by a standard single dose of PPV23 (the ''unprimed'' group). Quantitative and...


Source: Vaccine Weekly (2008-10-22)

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