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Vaccine Weekly

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DNA Vaccines



Research from China Agricultural University in the area of DNA vaccines published



October 22nd, 2008

Fresh data on dna are presented in the report 'Protein/DNA vaccine-induced antigen-specific Treg confer protection against asthma.' "Asthma is a chronic inflammatory disorder caused by T-cell-mediated inflammation within airways. No antigen-specific treatment has been available," scientists writing in the European Journal of Immunology report.

"Using an OVA-induced murine asthma model, we find that co-immunization of an OVA epitope peptide with a DNA vaccine encoding the same epitope is able to prevent this experimental asthma as evidenced in the marked reduction of infiltrations of eosinophils and lymphocytes into the site of the allergen challenge. We...


Source: Vaccine Weekly (2008-10-22)

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