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Vaccine Weekly

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Immunization



Findings in immunization reported from McGill University, Institute of Parasitology



October 29th, 2008

Fresh data on immunization are presented in the report 'Chemically attenuated Plasmodium sporozoites induce specific immune responses, sterile immunity and cross-protection against heterologous challenge.' According to recent research from Sainte-Anne-de-Bellevue, Canada, "Vaccination with Plasmodium sporozoites attenuated by irradiation or genetic manipulation induces a protective immune response in rodent malaria models."

"Recently, vaccination with chemically attenuated P. berghei sporozoites (CAS) has also been shown to elicit sterile immunity in mice. Here we show that vaccination with CAS of P. yoelii also protects against homologous infection and...


Source: Vaccine Weekly (2008-10-29)

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