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Helicobacter pylori
New helicobacter pylori findings from Novartis published
October 29th, 2008
"Helicobacter pylori infection is among the most common human infections and the major risk factor for peptic disease and gastric cancer. Immunization with vaccines containing the H pylori vacuolating cytotoxin A (VacA), cytotoxin-associated antigen (CagA), and neutrophil-activating protein (NAP), alone or in combination, have been shown to prevent experimental infection in animals," scientists writing in the journal Gastroenterology report. "We sought to study the safety and immunogenicity of a vaccine consisting of recombinant VacA, CagA, and NAP given intramuscularly with aluminium hydroxide as an adjuvant to noninfected healthy subjects. This controlled,...
Source: Vaccine Weekly (2008-10-29)
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