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Leishmaniasis
New research on leishmaniasis from R.B.G. Azeredocoutinho and co-authors summarized
October 29th, 2008
According to a study from Brazil, "It is known that the same antigen can induce different immune responses, depending upon the way that it is presented to the immune system. The objective of this study was to compare cytokine responses of peripheral blood mononuclear cells (PBMC) from cutaneous leishmaniasis patients and subjects immunized with a first-generation candidate vaccine composed of killed Leishmania amazonensis promastigotes to a whole-cell promastigote antigen extract (La) and to the recombinant protein LACK (Leishmania analogue receptor for activated C kinase), both from L. amazonensis." "Thirty-two patients, 35 vaccinees and 13 healthy subjects without...
Source: Vaccine Weekly (2008-10-29)
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