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Vaccine Weekly

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Hepatitis E Virus



Data from W.P. Hu et al provide new insights into hepatitis E virus



November 5th, 2008

According to a study from People's Republic of China, "A new double-antigen sandwich-based enzyme-linked immunosorbent assay (ELISA) for the detection of total antibodies (immunoglobulin G [IgG] and IgM) specific for hepatitis E virus (HEV) was developed by utilizing well-characterized recombinant protein ET2.1 and its peroxidase-labeled counterpart. Our study showed that the ELISA detected all the positive patient samples (n = 265) regardless of whether they contained IgM or IgG antibodies, or both, while it maintained an excellent specificity of 98.8% with samples from various patient or healthy control groups (total number of samples, 424)."

"The test had a detection...


Source: Vaccine Weekly (2008-11-05)

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