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Vaccine Weekly

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Herpesvirus



Studies from University of Nebraska further understanding of herpesvirus



November 5th, 2008

According to recent research published in the journal Clinical and Vaccine Immunology, "Human herpesvirus 8 (HHV-8), or Kaposi's sarcoma (KS)-associated herpesvirus, has been linked to all forms of KS. The results of most current serological assays for the detection of HHV-8-specific antibodies have low levels of concordance among themselves."

"To establish a sensitive and specific testing strategy that can be used to screen for HHV-8-specific antibodies, three HHV-8 proteins, ORF65, ORF73, and K8.1A, were expressed by using baculoviral vectors in insect cells and incorporated into a monoclonal antibody-enhanced immunofluorescence assay (mIFA) termed the Sf9...


Source: Vaccine Weekly (2008-11-05)

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