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Human Papillomavirus
Studies from University of Arkansas yield new data on human papillomavirus
November 5th, 2008
"Human papillomavirus (HPV)-specific T-cell response to the HPV type 16 (HPV16) E6 protein has beenshown to be associated with successful viral clearance. The patterns of CD8 T-cell epitopes within HPV16 E6 protein were previously studied in two women with HPV16 clearance," scientists writing in the journal Clinical and Vaccine Immunology report. "The goal of this study was to characterize these epitopes in terms of their minimal and optimal amino acid sequences and the human leukocyte antigen (HLA) restriction molecules. The presence of the epitope-specific memory T cells after viral clearance was also examined. In subject A, the dominant epitope was...
Source: Vaccine Weekly (2008-11-05)
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