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Vaccine Weekly

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Monoclonal Antibodies



New monoclonal antibodies study findings have been reported by F.R. Carvalho and colleagues



November 5th, 2008

"The present study aimed to evaluate the performance of three monoclonal antibodies (MAbs) in reverse enzyme-linked immunosorbent assays (ELISAs) for detecting immunoglobulin G (IgG), IgM, and IgA antibodies against Toxoplasma gondii in 175 serum samples from patients at different stages of T. gondii infection, as defined by both serological and clinical criteria, as follows: recent (n = 45), transient (n = 40), and chronic (n = 55) infection as well as seronegative subjects (n = 35). The results were compared with those obtained by indirect ELISA using soluble Toxoplasma total antigen (STAg)," researchers in Uberlandia, Brazil report.

"Our data demonstrated that MAb...


Source: Vaccine Weekly (2008-11-05)

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