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Vaccine Weekly

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Immunization



Reports outline immunization study results from Leiden University, Amsterdam Center for Drug Research



November 12th, 2008

Fresh data on immunization are presented in the report 'In vivo assessment of safety of microneedle arrays in human skin.' "Microneedle arrays are promising devices for the delivery of drugs and vaccines into or the skin. However, little is known about the safety of the microneedles," scientists in Leiden, Netherlands report.

"In this study we obtained insight in the ability of microneedles to disrupt the skin barrier, which was evaluated by transepidermal water loss (TEWL). We also determined the safety in terms of skin irritation (skin redness and blood flow) and pain sensation. We applied microneedle arrays varying in length and shape on the ventral forearms of 18...


Source: Vaccine Weekly (2008-11-12)

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