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Immunization
Researchers from University of North Carolina discuss findings in immunization
November 12th, 2008
Investigators publish new data in the report 'The contribution of type I interferon signaling to immunity induced by alphavirus replicon vaccines.' "The type I interferon (IFN) system is critical for protecting the mammalian host from numerous virus infections and plays a key role in shaping the antiviral adaptive immune response. In this report, the importance of type I IFN signaling was assessed in a mouse model of alphavirus-induced humoral immune induction," researchers in the United States report. "Venezuelan equine encephalitis virus replicon particles (VRP) expressing the hemagglutinin (HA) gene from influenza virus (HA-VRP) were used to vaccinate both wildtype...
Source: Vaccine Weekly (2008-11-12)
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