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Influenza Vaccines
New findings from University of Melbourne in the area of influenza vaccines published
November 12th, 2008
Scientists discuss in 'Sindbis virus vectors elicit hemagglutinin-specific humoral and cellular immune responses and offer a dose-sparing strategy for vaccination' new findings in influenza. "We report here on the use of a Sindbis virus-based DNA-launch RNA replicon vector (pSIN-HA) that expresses influenza hemagglutinin (HA) as an immunogen. Immunization of mice with pSIN-HA generated anti-HA antibody and CTL responses and resulted in lower lung viral titers after influenza challenge when compared to controls," researchers in Parkville, Australia report. "Importantly, immunization with a low dose of pSIN-HA mediated significantly reduced lung viral titers following...
Source: Vaccine Weekly (2008-11-12)
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