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Tuberculosis Vaccines



Research on tuberculosis vaccines detailed by scientists at Hamamatsu University, Department of Internal Medicine



November 12th, 2008

New investigation results, 'Intratracheal administration of third-generation lentivirus vector encoding MPT51 from Mycobacterium tuberculosis induces specific CD8+ T-cell responses in the lung,' are detailed in a study published in Vaccine. "The present study evaluates the potential of improved third-generation lentivirus vector with respect to their use as an in vivo-administered T-cell vaccine against tuberculosis. Intratracheal administration of the lentivirus vector encoding MPT51 of Mycobacterium tuberculosis could induce MPT51-specific CD8+ T cells in the mediastinal lymph nodes 2 weeks after the administration," scientists writing in the journal Vaccine...


Source: Vaccine Weekly (2008-11-12)

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