Pneumococcal Disease

New pneumococcal disease research from B. Simell and co-researchers described

Published in Vaccine Weekly, November 19th, 2008

"Elderly individuals are susceptible to pneumococcal infections. Although factors contributing to the increased susceptibility of the elderly to bacterial infections may be several, compromised immune function, a consequence of normal human aging, is widely accepted to play a role," investigators in Helsinki, Finland report.

"We evaluated the effect of aging on the concentrations of naturally acquired antibodies to pneumococcal capsular polysaccharides (PPS) and protein antigens. The concentrations of immunoglobulin G (IgG) and IgM antibodies to the PPS of serotypes 3, 4, 6B, 9V, 14, and 23F and IgG antibodies to the pneumococcal virulence-associated proteins CbpA,...

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Source: Vaccine Weekly (2008-11-19)

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