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Massachusetts Institute of Technology

MIT captures single-cell response to vaccination

Published in Vaccine Weekly, November 19th, 2008

MIT engineers have painted the most detailed portrait yet of how single cells from the immune system respond to vaccination.

The work, reported in the online edition of the Proceedings of the National Academy of Sciences the week of Nov. 3, could help researchers develop and test new vaccines for diseases including HIV, fungal infections and antibiotic-resistant bacterial infections.

"We're building a toolkit which we can use to look at how an immune response develops successfully. Then we aim to use that information for reverse engineering vaccines that would invoke that same type of response," said J. Christopher Love, assistant professor of...

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