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Strep Infection
New findings in strep infection described from Soroka University
November 26th, 2008
According to recent research published in the journal International Immunology, "The role of IL-1 in susceptibility to Streptococcus pneumoniae infection was studied in mice deficient in genes of the IL-1 family [i.e. IL-1 alpha(-/-), IL-1 beta(-/-), IL-1 alpha/beta(-/-) and IL-1R antagonist (IL-1Ra)(-/-) mice] following intra-nasal inoculation." "Intra-nasal inoculation of S. pneumoniae of IL-1 beta(-/-) and IL-1 alpha/beta(-/-) mice displayed significantly lower survival rates and higher nasopharyngeal and lung bacterial load as compared with control, IL-1 alpha(-/-) and IL-1Ra(-/-) mice. Treatment of IL-1 beta(-/-) mice with rIL-1 beta significantly improved...
Source: Vaccine Weekly (2008-11-26)
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