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Vaccine Weekly

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Hepatitis C Virus



Data on hepatitis C virus discussed by researchers at National Institutes of Health



November 26th, 2008

"Peripheral blood T-cell responses are used as biomarkers in hepatitis C virus (HCV) vaccine trials," scientists writing in the Journal of Virology report.

"However, it is not clear how T-cell responses in the blood correlate with those in the liver, the infection site. By studying serial liver and blood samples of five vaccinated and five mock-vaccinated control chimpanzees during acute HCV infection, we demonstrate a correlation between HCV-specific CD8 T-cell responses in the blood and molecular and functional markers of T-cell responses in the liver," wrote E.C. Shin and colleagues, National Institutes of Health.

The researchers concluded:...


Source: Vaccine Weekly (2008-11-26)

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