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Vaccine Weekly

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Peptide Synthesis



Studies from University of Firenze have provided new data on peptide synthesis



December 3rd, 2008

Investigators publish new data in the report 'Advances in automatic, manual and microwave-assisted solid-phase peptide synthesis.' "Solid-phase strategies speed up the production of both short-and long-sequence peptides compared with solution methodologies. Therefore, solid-phase peptide synthesis (SPPS), proposed by Merrifield in the early 1960s, contributed to the 'Peptide Revolution' in the fields of diagnostics, and drug and vaccine development," scientists in Italy report.

"Since then, peptide chemistry research has aimed to optimize these synthetic procedures, focusing on areas such as amide bond formation (the coupling step), solid supports and automation....


Source: Vaccine Weekly (2008-12-03)

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