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Cancer Vaccines
Studies from J. Fourcade and co-authors have provided new information about cancer vaccines
December 3rd, 2008
According to recent research from the United States, "Analog peptides represent a promising tool to further optimize peptide-based vaccines in promoting the expansion of tumor antigen-specific cytotoxic T lymphocytes. Here, we report the results of a pilot trial designed to study the immunogenicity of the analog peptide NY-ESO-1157-165V in combination with CpG 7909/PF3512676 and Montanide ISA 720 in patients with stage III/IV NY-ESO-1-expressing melanoma." "Eight patients were immunized either with Montanide and CpG (arm 1, 3 patients); Montanide and peptide NY-ESO-1 157-165V (arm 2, 2 patients) or with Montanide, CpG, and peptide NY-ESO-1 157-165V farm 3, 3 patients)....
Source: Vaccine Weekly (2008-12-03)
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