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Vaccine Weekly

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HIV/AIDS



New HIV/AIDS study findings have been reported from A. Piantadosi et al



December 3rd, 2008

According to recent research from the United States, "HIV-1 superinfection may occur at a rate similar to that of initial infection, raising concerns for HIV-1 vaccine strategies predicated on eliciting immune responses similar to those in natural infection. Because of the high rate of recombination during HIV-1 replication, studies examining only one region of the HIV-1 genome are likely to miss cases of HIV-1 superinfection."

"We examined HIV-1 gag sequences from 14 high-risk Kenyan women in whom superinfection was not detected in a previous study of env sequences. We detected two additional cases of HIV-1 superinfection: one intersubtype superinfection that occurred...


Source: Vaccine Weekly (2008-12-03)

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