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Cancer Gene Therapy
Data on cancer gene therapy detailed by researchers at Sapporo Medical University, Department of Urology
December 3rd, 2008
New research, 'Identification of an immunogenic CTL epitope of HIFPH3 for immunotherapy of renal cell carcinoma,' is the subject of a report. According to recent research from Sapporo, Japan, "CD8(+) CTLs have an essential role in immune response against tumor. Although tumor-associated antigens have been identified in renal cell carcinoma (RCC), few of these are commonly shared and investigated as therapeutic targets in the clinical medicine." "In this report, we show that HIFPH3, a member of prolyl hydroxylases that function as oxygen sensor, is a novel tumor antigen and HIFPH3-specific CTLs are induced from peripheral blood lymphocytes of RCC patients. Expression of...
Source: Vaccine Weekly (2008-12-03)
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