Immunization

New immunization findings from Erasmus University described

Published in Vaccine Weekly, December 3rd, 2008

According to recent research published in the Journal of Immunology, "The role of specific CD4(+) T cell subsets in the induction of Immoral immune responses in humans is largely unknown. In this study, the generation of hepatitis B surface Ag-specific CD4(+) T lymphocytes following vaccination was closely monitored and characterized at the single-cell level."

"The appearance and absolute numbers of hepatitis B surface Ag-specific IL-2 producing effector memory CD4(+) T lymphocytes was solely and tightly related to Ab titers reached. This relation remained present many years after vaccination. Subsequently, a relation was found between Ab titers and number of...

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Source: Vaccine Weekly (2008-12-03)

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