Vaccine Weekly
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Vaccine Weekly
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Immunization
Scientists at University of Antwerp target immunization
December 3rd, 2008
According to recent research from Antwerp, Belgium, "The trematode Fasciola hepatica (Fa. he.) is a common parasite of human and livestock. The hemoglobin (Hb) of Fa. he., a potential immunogen, was chosen for characterization in the search for an effective vaccine." "Characterization of trematode Hbs show that they are intracellular single-domain globins with the following remarkable features: (1) Fa. he. expresses two Hb isoforms that differ at two amino acid sites (F1: 119Y/123Q; F2: 119F/123L). Both isoforms are monoacetylated at their N-termini; (2) the genes coding for Fa. he. and Paramphistomum epiclitum (Pa. ep.) Hbs are interrupted by two introns at the...
Source: Vaccine Weekly (2008-12-03)
|
