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Vaccine Weekly

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Tuberculosis



Recent findings in tuberculosis described by C.P. Bhunu and colleagues



December 10th, 2008

"Epidemic control strategies alter the spread of the disease in the host Population. In this paper, we describe and discuss mathematical models that can be used to explore the potential of pre-exposure and post-exposure vaccines currently under development in the control of tuberculosis," researchers in Bulawayo, Zimbabwe report.

"A model with bacille Calmette-Guerin (BCG) vaccination for the susceptibles and treatment for the infectives is first presented. The epidemic thresholds known as the basic reproduction numbers and equilibria for the models are determined and stabilities are investigated. The reproduction numbers for the models are compared to assess the impact...


Source: Vaccine Weekly (2008-12-10)

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