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Vaccine Weekly

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Immunology



Study data from King's College London, King's College London update understanding of immunology



December 10th, 2008

Data detailed in 'Freeze-and-thaw-disrupted tumour cells impair the responsiveness of DC to TLR stimulation' have been presented. According to a study from London, the United Kingdom, "Cancer immunotherapy aims at inducing immune responses against tumour-associated antigens that mediate the eradication of tumor cells. For successful vaccination against antigens expressed by the tumour, the immune system has to be provided with sufficient amounts of these antigens in connection with strong immunostimulatory signals such as toll-like receptor (TLR) ligands."

"Tumour cells represent a convenient source of relevant tumour-associated antigens but can have suppressive...


Source: Vaccine Weekly (2008-12-10)

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