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Vaccine Weekly

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Gene Therapy



New gene therapy study findings have been reported from Texas A&M University



December 10th, 2008

According to recent research published in the Journal of Experimental Biology, "The organic anion transporting polypeptides (Oatps in rodents and other organism; OATPs in human) are Na+-independent transporters that shuttle a wide range of endogenous and xenobotic amphipathic compounds across plasma membranes. We previously discovered an Amblyomma americanum tick (Aam) Oatp cDNA among genes that were upregulated or induced in ticks that were stimulated to start feeding."

"In this study, we have characterized a 2860 bp full-length cDNA that encode a 724 amino acid putative protein. Bioinformatics and hydropathy analyses revealed that, in addition to the kazal-type...


Source: Vaccine Weekly (2008-12-10)

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