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Vaccine Weekly

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Hepatitis C Virus



Researchers' work from Kurume University, Medical Department focuses on hepatitis C virus



December 17th, 2008

"The determination of immunogenic peptides of hepatitis C virus (HCV) is pivotal for vaccine development. We previously reported that the majority of patients infected with HCV have significant levels of IgG specific to an HCV-derived peptide at positions 35-44 of core protein (C35-44), a major epitope recognized by cellular immunity," scientists in Kurume, Japan report.

"This study addresses whether or not the other subclasses of immunoglobulins to this peptide exist. As a result, IgE, but not IgM or IgA, specific to this peptide is consistently detectable in the majority of patients with HCV infection, regardless of the different HLA types and disease conditions,"...


Source: Vaccine Weekly (2008-12-17)

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