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Life Sciences
Investigators at University of California publish new data on life sciences
December 17th, 2008
According to recent research from the United States, "Acid-degradable particles containing a model protein antigen, ovalbumin, were prepared from a polyurethane with acetal moieties embedded throughout the polymer, and characterized by dynamic light scattering and transmission electron microscopy. The small molecule degradation byproduct of the particles was synthesized and tested in vitro for toxicity indicating an LC50 of 12,500 mu g/mL." "A new liquid chromatography-mass spectrometry technique was developed to monitor the in vitro degradation of these particles. The degradation byproduct inside RAW macrophages was at its highest level after 24 h of culture and was...
Source: Vaccine Weekly (2008-12-17)
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