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Pneumococcal Disease
Research on pneumococcal disease reported by J. Villena et al
December 17th, 2008
According to a study from Chacabuco, Argentina, "In the present work, we evaluated if oral immunization with the pneumococcal protective protein A (PppA), expressed in the cell wall of Lactococcus lactis (L.alactis PppA+), was able to confer protective immunity against Streptococcus pneumoniae. Mice were immunized orally with L.alactis PppA+ for 5 consecutive days." "Vaccination was performed one (nonboosted group) or 2 times with a 2 week interval between each immunization (boosted group). Oral priming with L.alactis PppA+ induced the production of anti-PppA IgM, IgG, and IgA antibodies in serum and in bronchoalveolar (BAL) and intestinal (IF) lavage fluids. Boosting...
Source: Vaccine Weekly (2008-12-17)
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