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Cholera Vaccines



New research on cholera vaccines from Research Center for Infectious Diseases summarized



December 17th, 2008

New investigation results, 'Construction of a Vibrio cholerae prototype vaccine strain O395-N1-E1 which accumulates cell-associated cholera toxin B subunit,' are detailed in a study published in Vaccine. According to recent research from Seoul, Korea, "Because of its production and use in Vietnam, the most widely used oral cholera vaccine consists of heat-or formalin-killed Vibrio cholerae whole cells (WC). An earlier version of this type of vaccine called whole cell-recombinant B subunit vaccine (BS-WC) produced in Sweden also contained the B subunit of cholera toxin (CTB)."

"Both WC and BS-WC vaccines produced moderate levels of protection in field...


Source: Vaccine Weekly (2008-12-17)

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