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Foot and Mouth Disease Vaccines
Report summarizes foot and mouth disease vaccines study findings from Lanzhou Veterinary Research Institute
December 17th, 2008
A new study, 'A novel bi-functional DNA vaccine expressing VP1 protein and producing antisense RNA targeted to 5'UTR of foot-and-mouth disease virus can induce both rapid inhibitory effect and specific immune response in mice,' is now available. "To overcome the inability of a conventional vaccine against a virus to induce rapid protection against viral challenge, a novel strategy was performed to generate a novel bi-functional vector expressing antisense RNA targeted to 5' untranslated regions (UTR) and VP1 protein of foot-and-mouth disease virus (FMDV). FMDV 5'UTR containing the viral RNA replication start elements was inserted inversely into the pIRES vector to produce antisense RNA,...
Source: Vaccine Weekly (2008-12-17)
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