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Leishmaniasis Vaccines



Studies from Pasteur Institute of Iran yield new data on leishmaniasis vaccines



December 17th, 2008

Investigators publish new data in the report 'Cysteine proteinase type III is protective against Leishmania infantum infection in BALB/c mice and highly antigenic in visceral leishmaniasis individuals.' "Visceral leishmaniasis is the most acute form of leishmaniasis and vaccination is the best approach to control it. One of the major groups of virulence factors in Leishmania belongs to cysteine proteinase family," scientists writing in the journal Vaccine report.

"In this study, for the first time, the protective potential of Leishmania infantum cysteine proteinase type III (CPC) by using a prime-boost strategy is evaluated in BALB/c mice. The experiment...


Source: Vaccine Weekly (2008-12-17)

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